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CORRELATION BETWEEN OSA, ANTROMETRIC DATA AND PULMONARY FUNCTION IN MORBID OBESE
Obstructive sleep apnea (OSA) is characterized by recurrent airway closure during sleep, causing hypoxia, hypercapnia and frequent awakenings. Obesity predisposes and enhances OSA risk, and it is also the most susceptible to reversibility. The reverse is also true – the obese individual with fragmented sleep, typical of OSA, will present hormone deficiency related to satiety and appetite, aggravating weight gain and difficulty in weight loss. The main treatment to improve both conditions is weight loss, which is sometimes only achieved through bariatric surgery.
The purpose of this study is to describe the clinical profile, identify the prevalence of OSAS, verify the presence of comorbidities and to evaluate the pulmonary function in obese patients prior to the bariatric surgery.
The studied population is composed of adults, over 18 years of age of both genders. They will be submitted to the Berlin Questionnaire (QB), for the diagnosis of OSAS, and to the Epworth Sleepiness Scale (ESS), to identify excessive daytime sleepiness, as well as pulmonary function tests such as spirometry and manovacuometry, to measure values of forced vital capacity (FVC), forced expiratory volume in one second (FEV1), forced expiratory flow (FEF), maximal inspiratory and expiratory pressure (MIP and MEP, respectively).
Seventy-six outpatients were evaluated, of which 64 are women and 13 are men. The studied group had a mean age of 41,8 ± 11,6 years and a mean BMI of 47.10 ± 7.3 kg/m², the majority (90%) being classified as grade III obesity. 65,8% of the participants affirmed to have hypertension, 23,7% mellitus diabetes II and 19,7%, both. Of the respondents, 90.8% presented a high risk for OSAS by QB and 49 of them had positive daytime sleepiness according to the ESS. After the spirometry test, the subjects had mean FVC of 3,4 ± 0,9 L/s, FEV1 of 97,3 ± 3,3 L/s. and FEF 341,8 ± 92,5 L/s Also, they presented mean MIP values of -104,70 ± 19,4 cmH20 (106% of predicted value) and mean MEP of 95,1 ± 18,9 (99% of predicted value).
The individuals evaluated have high risk of OSA, with high percentage of hypertension with excessive daytime sleepiness, however, their pulmonary function tests were regular.
Sleep apnea. Obesity. OSAS. Pulmonary function. Bariatric surgery.
Fernanda BUTURA BROETTO, CAROLINA DE PAULA FERRAZ SOARES, MARCELO TAGLIETTI, JENANE TOPANOTTI, ANDRESSA PIRES ALVES, LUCIANE LOPES, MICHELI SIGNOR, PATRICIA FREITAG FERREIRA, VANESSA CARLA TRENTIM, LARISSA MARIANE CÔCCO