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2 years Follow-up of Occlusal and skeletal changes in obstructive sleep apnea patients treated with oral appliance with mandibular advancement.


According to clinical practice recommendations, Oral Appliance Therapy (OAT) of Obstructive Sleep Apnea (OSA) should be monitored and supervised for dental side effects or occlusal changes. However, little research is found in the literature addressing the monitoring and supervision of these patients.
The Oral Appliance with mandibular advancement (OAm) makes considerable advances in design, construction techniques, and individualization capacity, but the stomatognathic system anatomy and physiology are still not taken into consideration. Due to these concepts, the OAm can further impact therapy effectiveness by maintaining the stomatognathic system in functional balance with minimal structures interference. The traditional construction of the OAm is performed on dental arch models with occlusal plane transfer to superior base, where OAm construction is oriented without considering the orthogonal planes. In addition, the traditional construction disrupts standard monitoring and supervision of side effects related to dental arches related with skeletal structures. In order to generate reliable scientific evidence and standardized data, the gnathostatic model that uses the Camper plane transfer to a superior model base may prove to be a useful tool, from occlusal plane diagnosis with three-dimensional skeletal references, to the OAm construction, and OAT follow-up.


Thus, a retrospective longitudinal study will be conducted with patients treated for OSA based on the gnathostatic model, measuring occlusal and skeletal changes, along with assessing the OAT with follow-up for 2 or more years.


The study will be conducted based on a random sample composed of medical records of patients who have been using OAm in dental clinics to treat OSA with objective and subjective data. Access to dental records will be equipped with clinics collaboration, patient’s permission at research participation and Informed Consent. The sample size calculated was 34 based on the Student test application for paired data.


Without results


Without conclusion


Obstructive sleep apnea, oral appliance therapy, neuro occlusal rehabilitation, follow-up, side effects, long term.




FOP - UNICAMP - Sao Paulo - Brasil


Denise Fernandes Barbosa, Miguel Gonçalves Meira e Cruz, Marcelo Corrêa Alves, Fausto Berzin